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Hypoxia-Inducible Factor Activators Xenon and Argon added to the 2014 Prohibited List

The World Anti-Doping Code Prohibited List has been updated to include Xenon and Argon

The World Anti-Doping Code Prohibited List has been updated to include Xenon and Argon

Hypoxia-Inducible Factor (HIF) activators Xenon and Argon have been added to the World Anti-Doping Code Prohibited List, effective from 1 September 2014.

Both are prohibited under section S2 Peptide Hormones, Growth Factors and Related Substances, banned for use in and out-of-competition. The change is made following recommendation at the April World Anti-Doping Agency (WADA) List Committee meeting and the conclusion of the required three-month notice period.

The change to the List reads as follows:

S2. PEPTIDE HORMONES, GROWTH FACTORS AND RELATED SUBSTANCES

The following substances, and other substances with similar chemical structure or similar biological effect(s), are prohibited:

1. Erythropoiesis-Stimulating Agents [e.g. erythropoietin (EPO), darbepoetin (dEPO), hypoxia-inducible factor (HIF) stabilizers and activators (e.g. xenon, argon), methoxy polyethylene glycol-epoetin beta (CERA), peginesatide (Hematide)]

The revised 2014 Prohibited List can be found in the Resources area while WADA has produced an online Explanatory Note.

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