Protecting the Right to Enjoy Doping-Free Sport


WADA issues alert on substance GW501516

The World Anti-Doping Agency (WADA) has issued the following statement alerting the athlete community to the risks associated with prohibited substance GW501516:

It has come to WADA’s attention that the black market substance GW501516 is being sold to and used by some athletes.

The side effect of this chemical compound is so serious that WADA is taking the rare step of warning “cheats” to ensure that there is complete awareness of the possible health risks to athletes who succumb to the temptation of using GW501516 for performance enhancement.

GW501516 was a developmental drug that was withdrawn from research by the pharmaceutical company and terminated when serious toxicities were discovered in pre-clinical studies. Clinical approval has not, and will not be given for this substance.

However, GW501516 has been available for some months on the black market, through the Internet and elsewhere. Anti-Doping authorities have already seen its use by athletes, as there are a number of positive cases.

Please pass this information on to your athletes as soon as possible.

GW501516 has been included on WADA's List of Prohibited Substances and Methods since 2009. Since 2012 it has been prohibited under category S4-5b, Peroxisome Proliferator Activated Receptor δ (PPARδ) agonists.

GW501516 can be referred to under different names, including GW501, GW516, GW1516 and Endurobol.